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抗性DNA在水土环境中的迁移归趋与水平转移

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赵方园, 杨新瑶, 陈芳敏, 阮丽丽, 张海燕, 杨悦锁. 抗性DNA在水土环境中的迁移归趋与水平转移[J]. 环境化学, 2018, 37(8): 1804-1819. doi: 10.7524/j.issn.0254-6108.2018022701
引用本文: 赵方园, 杨新瑶, 陈芳敏, 阮丽丽, 张海燕, 杨悦锁. 抗性DNA在水土环境中的迁移归趋与水平转移[J]. 环境化学, 2018, 37(8): 1804-1819. doi: 10.7524/j.issn.0254-6108.2018022701
shu
ZHAO Fangyuan, YANG Xinyao, CHEN Fangmin, RUAN Lili, ZHANG Haiyan, YANG Yuesuo. Transport, fate and horizontal transfer of antibiotic resistance DNA in soil and water environment[J]. Environmental Chemistry, 2018, 37(8): 1804-1819. doi: 10.7524/j.issn.0254-6108.2018022701
Citation: ZHAO Fangyuan, YANG Xinyao, CHEN Fangmin, RUAN Lili, ZHANG Haiyan, YANG Yuesuo. Transport, fate and horizontal transfer of antibiotic resistance DNA in soil and water environment[J]. Environmental Chemistry, 2018, 37(8): 1804-1819. doi: 10.7524/j.issn.0254-6108.2018022701
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抗性DNA在水土环境中的迁移归趋与水平转移

  • 1.

    沈阳大学环境学院区域污染环境生态修复教育部重点实验室, 沈阳, 110044;

  • 2.

    沈阳大学生命科学与工程学院辽宁省城市有害生物治理与生态安全重点实验室, 沈阳, 110044;

  • 3.

    黑龙江省水文地质工程地质勘察院, 哈尔滨, 150030

  • 基金项目:

    国家自然科学基金（41672248，41471409）和黑龙江国土厅科技项目和辽宁省创新团队（LT2015017）资助.

Transport, fate and horizontal transfer of antibiotic resistance DNA in soil and water environment

  • 1.

    Ministry of Education Key Lab for Eco-restoration of Regional Contaminated Environment, School of Environment, Shenyang University, Shenyang, 110044, China;

  • 2.

    Liaoning Key Lab of Urban IPM and Eco-security, School of Life Science and Engineering, Shenyang University, Shenyang, 110044, China;

  • 3.

    Hydrogeology Exploration Institute of Heilongjiang, Harbin, 150030, China

  • Fund Project: Supported by the National Natural Science Foundation of China (41672248,41471409) and Science Foundation of Department of Land and Resources of Heilongjiang Province,Innovation Team Foundation of Liaoning Province(LT2015017).

  • 摘要: 抗性基因是与抗生素的滥用密切关联的一种新型环境污染物.DNA作为抗性基因的载体，其在环境中的赋存、迁移与水平转移对于环境中抗药性的传播十分重要.基于文献，本文针对与抗药性传播密切关联的各个环节，系统讨论了环境因子对DNA分子的损伤、保护和修复等影响DNA的赋存与归趋的机制，DNA吸附、解吸与迁移等影响其在环境中移动性的机制，以及水平转移等引发细菌产生抗药性的机制.文末提出了值得进一步研究的科学问题.
    Abstract: Antibiotic resistance gene (ARG) is an emerging environmental contaminant closely related to the abuse of antibiotics. DNA as a carrier of ARG, its occurrence, transport and horizontal transfer govern the spread of the ARG in the broad environment. This paper reviewed the literature related to the above processes and comprehensively discussed the environmental factors and mechanisms related to DNA occurrence and fate such as DNA damaging, protection and repair. DNA mobility such as adsorption, desorption and transport. Incurrence of antibiotic resistance such as horizontal transfer. In the end, scientific questions that merit further study were proposed.
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  • 收稿日期:  2018-02-27
  • 刊出日期:  2018-08-15
赵方园, 杨新瑶, 陈芳敏, 阮丽丽, 张海燕, 杨悦锁. 抗性DNA在水土环境中的迁移归趋与水平转移[J]. 环境化学, 2018, 37(8): 1804-1819. doi: 10.7524/j.issn.0254-6108.2018022701
引用本文: 赵方园, 杨新瑶, 陈芳敏, 阮丽丽, 张海燕, 杨悦锁. 抗性DNA在水土环境中的迁移归趋与水平转移[J]. 环境化学, 2018, 37(8): 1804-1819. doi: 10.7524/j.issn.0254-6108.2018022701
shu
ZHAO Fangyuan, YANG Xinyao, CHEN Fangmin, RUAN Lili, ZHANG Haiyan, YANG Yuesuo. Transport, fate and horizontal transfer of antibiotic resistance DNA in soil and water environment[J]. Environmental Chemistry, 2018, 37(8): 1804-1819. doi: 10.7524/j.issn.0254-6108.2018022701
Citation: ZHAO Fangyuan, YANG Xinyao, CHEN Fangmin, RUAN Lili, ZHANG Haiyan, YANG Yuesuo. Transport, fate and horizontal transfer of antibiotic resistance DNA in soil and water environment[J]. Environmental Chemistry, 2018, 37(8): 1804-1819. doi: 10.7524/j.issn.0254-6108.2018022701
shu

抗性DNA在水土环境中的迁移归趋与水平转移

  • 1.  沈阳大学环境学院区域污染环境生态修复教育部重点实验室, 沈阳, 110044;
  • 2.  沈阳大学生命科学与工程学院辽宁省城市有害生物治理与生态安全重点实验室, 沈阳, 110044;
  • 3.  黑龙江省水文地质工程地质勘察院, 哈尔滨, 150030
  • 收稿日期:  2018-02-27
基金项目:

国家自然科学基金（41672248，41471409）和黑龙江国土厅科技项目和辽宁省创新团队（LT2015017）资助.

摘要: 抗性基因是与抗生素的滥用密切关联的一种新型环境污染物.DNA作为抗性基因的载体，其在环境中的赋存、迁移与水平转移对于环境中抗药性的传播十分重要.基于文献，本文针对与抗药性传播密切关联的各个环节，系统讨论了环境因子对DNA分子的损伤、保护和修复等影响DNA的赋存与归趋的机制，DNA吸附、解吸与迁移等影响其在环境中移动性的机制，以及水平转移等引发细菌产生抗药性的机制.文末提出了值得进一步研究的科学问题.

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