[1] BENGTSSON-PALME J, LARSSON D G J. Concentrations of antibiotics predicted to select for resistant bacteria: Proposed limits for environmental regulation[J]. Environment International, 2016, 86: 140-149. doi: 10.1016/j.envint.2015.10.015
[2] ZHANG Y, WALSH T R, WANG Y, et al. Minimizing risks of antimicrobial resistance development in the environment from a public one health perspective[J]. China CDC Weekly, 2022, 4(49): 1105-1109. doi: 10.46234/ccdcw2022.224
[3] 李超. 制药产业国际竞争力关键因素与形成机理研究[D]. 北京: 中国政法大学, 2020.
[4] HAN Z M, ZHANG Y, YANG M. Deterring the transmission of amr in the environment: A chinese perspective. Handbook on antimicrobial resistance: current status, trends in detection and mitigation measures[EB/OL]. [2023-04-22].https://link.springer.com/referenceworkentry/10.1007/978-981-16-9723-4_52-1.
[5] LARSSON D G J, FLACH C F. Antibiotic resistance in the environment[J]. Nature Reviews Microbiology, 2021, 20(5): 257-269.
[6] ZHANG Y, XIE J P, LIU M M, et al. Microbial community functional structure in response to antibiotics in pharmaceutical wastewater treatment systems[J]. Water Research, 2013, 47(16): 6298-6308. doi: 10.1016/j.watres.2013.08.003
[7] MA W L, QI R, ZHANG Y, et al. Performance of a successive hydrolysis, denitrification and nitrification system for simultaneous removal of COD and nitrogen from terramycin production wastewater[J]. Biochemical Engineering Journal, 2009, 45(1): 30-34. doi: 10.1016/j.bej.2009.02.001
[8] ZHANG Q Q, YING G G, PAN C G, et al. Comprehensive evaluation of antibiotics emission and fate in the river basins of china: Source analysis, multimedia modeling, and linkage to bacterial resistance[J]. Environmental Science & Technology, 2015, 49(11): 6772-6782.
[9] LI D, QI R, YANG M, et al. Bacterial community characteristics under long-term antibiotic selection pressures[J]. Water Research, 2011, 45(18): 6063-6073. doi: 10.1016/j.watres.2011.09.002
[10] 张昱, 冯皓迪, 唐妹, 等. β-内酰胺类抗生素的环境行为与制药行业源头控制技术研究进展[J]. 环境工程学报, 2020, 14(8): 1993-2010.
[11] CHENG D L, NGO H H, GUO W S, et al. Anaerobic membrane bioreactors for antibiotic wastewater treatment: Performance and membrane fouling issues[J]. Bioresource Technology, 2018, 267: 714-724. doi: 10.1016/j.biortech.2018.07.133
[12] CHENG D L, NGO H H, GUO W S, et al. Bioprocessing for elimination antibiotics and hormones from swine wastewater[J]. Science of The Total Environment, 2018, 621: 1664-1682. doi: 10.1016/j.scitotenv.2017.10.059
[13] ENIOLA J O, KUMAR R, BARAKAT M A, et al. A review on conventional and advanced hybrid technologies for pharmaceutical wastewater treatment[J]. Journal of Cleaner Production, 2022, 356.
[14] 刘玮. 2级厌氧反应器处理发酵类抗生素废水[J]. 水处理技术, 2018, 144(7): 78-81.
[15] MENG L W, LI X K, WANG K, et al. Influence of the amoxicillin concentration on organics removal and microbial community structure in an anaerobic egsb reactor treating with antibiotic wastewater[J]. Chemical Engineering Journal, 2015, 274: 94-101. doi: 10.1016/j.cej.2015.03.065
[16] SHI X, LEONG K Y, NG H Y. Anaerobic treatment of pharmaceutical wastewater: A critical review[J]. Bioresource Technology, 2017, 245(Pt A): 1238-1244.
[17] YI Q Z, ZHANG Y, GAO Y X, et al. Anaerobic treatment of antibiotic production wastewater pretreated with enhanced hydrolysis: Simultaneous reduction of COD and ARGs[J]. Water Research, 2017, 110: 211-217. doi: 10.1016/j.watres.2016.12.020
[18] JU F, BECK K, YIN X L, et al. Wastewater treatment plant resistomes are shaped by bacterial composition, genetic exchange, and upregulated expression in the effluent microbiomes[J]. The ISME Journal, 2018, 13(2): 346-360.
[19] 程辉, 纪佳渊, 李玉友. 厌氧膜生物反应器及其应用研究实例[J]. 生物产业技术, 2019, 2: 15-27.
[20] LIAO B Q, KRAEMER J T, BAGLEY D M. Anaerobic membrane bioreactors: Applications and research directions[J]. Critical Reviews in Environmental Science and Technology, 2006, 36(6): 489-530. doi: 10.1080/10643380600678146
[21] CHENG H, HIRO Y, HOJO T, et al. Upgrading methane fermentation of food waste by using a hollow fiber type anaerobic membrane bioreactor[J]. Bioresource Technology, 2018, 267: 386-394. doi: 10.1016/j.biortech.2018.07.045
[22] LIN H J, CHEN J R, WANG F Y, et al. Feasibility evaluation of submerged anaerobic membrane bioreactor for municipal secondary wastewater treatment[J]. Desalination, 2011, 280(1/2/3): 120-126.
[23] ABUABDOU S M A, AHMAD W, AUN N C, et al. A review of anaerobic membrane bioreactors (AnMBR) for the treatment of highly contaminated landfill leachate and biogas production: Effectiveness, limitations and future perspectives[J]. Journal of Cleaner Production, 2020, 255: 120215. doi: 10.1016/j.jclepro.2020.120215
[24] LI S N, ZHANG C F, LI F X, et al. Technologies towards antibiotic resistance genes (ARGs) removal from aquatic environment: A critical review[J]. Journal of Hazardous Materials, 2021, 411: 125148. doi: 10.1016/j.jhazmat.2021.125148
[25] OBEROI A S, SURENDRA K C, WU D, et al. Anaerobic membrane bioreactors for pharmaceutical-laden wastewater treatment: A critical review[J]. Bioresource Technology, 2022, 361: 127667. doi: 10.1016/j.biortech.2022.127667
[26] WU Q D, ZOU D S, ZHENG X C, et al. Effects of antibiotics on anaerobic digestion of sewage sludge: Performance of anaerobic digestion and structure of the microbial community[J]. Science of the Total Environment, 2022, 845: 157384. doi: 10.1016/j.scitotenv.2022.157384
[27] CHENG D L, NGO H H, GUO W S, et al. Problematic effects of antibiotics on anaerobic treatment of swine wastewater[J]. Bioresource Technology, 2018, 263: 642-653. doi: 10.1016/j.biortech.2018.05.010
[28] WANG G W, WANG D, XU X C, et al. Wet air oxidation of pretreatment of pharmaceutical wastewater by Cu2+ and [PxWmOy]q- co-catalyst system[J]. Journal of Hazardous Materials, 2012, 217: 366-373.
[29] OKTEM Y A, INCE O, SALLIS P, et al. Anaerobic treatment of a chemical synthesis-based pharmaceutical wastewater in a hybrid upflow anaerobic sludge blanket reactor[J]. Bioresource Technology, 2008, 99(5): 1089-1096. doi: 10.1016/j.biortech.2007.02.036
[30] CHEN Z B, XU J, HU D X, et al. Performance and kinetic model of degradation on treating pharmaceutical solvent wastewater at psychrophilic condition by a pilot-scale anaerobic membrane bioreactor[J]. Bioresource Technology, 2018, 269: 319-328. doi: 10.1016/j.biortech.2018.08.075
[31] ZHANG Y, TIAN Z, LIU M M, et al. High concentrations of the antibiotic spiramycin in wastewater lead to high abundance of ammonia-oxidizing archaea in nitrifying populations[J]. Environmental Science & Technology, 2015, 49(15): 9124-32.
[32] LUAN X, ZHANG H, TIAN Z, et al. Microbial community functional structure in an aerobic biofilm reactor: Impact of streptomycin and recovery[J]. Chemosphere, 2020, 255: 127032. doi: 10.1016/j.chemosphere.2020.127032
[33] MUNIR M, WONG K, XAGORARAKI I. Release of antibiotic resistant bacteria and genes in the effluent and biosolids of five wastewater utilities in michigan[J]. Water Research, 2011, 45(2): 681-693. doi: 10.1016/j.watres.2010.08.033
[34] RANI J, PANDEY KP, KUSHWAHA J, et al. Antibiotics in anaerobic digestion: Investigative studies on digester performance and microbial diversity[J]. Bioresource Technology, 2022, 361: 127662. doi: 10.1016/j.biortech.2022.127662
[35] VAN LIER J B. High-rate anaerobic wastewater treatment: Diversifying from end-of-the-pipe treatment to resource-oriented conversion techniques[J]. Water Science and Technology, 2008, 57(8): 1137-1148. doi: 10.2166/wst.2008.040
[36] TAO Y, GAO D W, FU Y, et al. Impact of reactor configuration on anammox process start-up: MBR versus SBR[J]. Bioresource Technology, 2012, 104: 73-80. doi: 10.1016/j.biortech.2011.10.052
[37] DERELI R K, ERSAHIN M E, OZGUN H, et al. Potentials of anaerobic membrane bioreactors to overcome treatment limitations induced by industrial wastewaters[J]. Bioresource Technology, 2012, 122: 160-70. doi: 10.1016/j.biortech.2012.05.139
[38] CHENG H, CHENG D, MAO J W, et al. Identification and characterization of core sludge and biofilm microbiota in anaerobic membrane bioreactors[J]. Environment International, 2019, 133: 105165. doi: 10.1016/j.envint.2019.105165
[39] HARB M, ZAREI-BAYGI A, WANG P, et al. Antibiotic transformation in an anaerobic membrane bioreactor linked to membrane biofilm microbial activity[J]. Environmental Research, 2021, 200: 111456. doi: 10.1016/j.envres.2021.111456
[40] MONSALVO V M, MCDONALD J A, KHAN S J, et al. Removal of trace organics by anaerobic membrane bioreactors[J]. Water Research, 2014, 49: 103-112. doi: 10.1016/j.watres.2013.11.026
[41] GONZALEZ-GIL L, MAURICIO-IGLESIAS M, SERRANO D, et al. Role of methanogenesis on the biotransformation of organic micropollutants during anaerobic digestion[J]. Science of the Total Environment, 2018, 622-623: 459-466. doi: 10.1016/j.scitotenv.2017.12.004
[42] CETECIOGLU Z, INCE B, ORHON D, et al. Anaerobic sulfamethoxazole degradation is driven by homoacetogenesis coupled with hydrogenotrophic methanogenesis[J]. Water Research, 2016, 90: 79-89. doi: 10.1016/j.watres.2015.12.013
[43] SAWAYA C B, HARB M. Considering the prospect of utilizing anaerobic membrane biofouling layers advantageously for the removal of emerging contaminants[J]. Frontiers in Chemical Engineering, 2021, 3: 642280. doi: 10.3389/fceng.2021.642280
[44] HARB M, WEI C H, WANG N, et al. Organic micropollutants in aerobic and anaerobic membrane bioreactors: Changes in microbial communities and gene expression[J]. Bioresource Technology, 2016, 218: 882-891. doi: 10.1016/j.biortech.2016.07.036
[45] JIA Y Y, KHANAL S K, ZHANG H Q, et al. Sulfamethoxazole degradation in anaerobic sulfate-reducing bacteria sludge system[J]. Water Research, 2017, 119: 12-20. doi: 10.1016/j.watres.2017.04.040
[46] JIA Y Y, ZHANG H Q, KHANAL S K, et al. Insights into pharmaceuticals removal in an anaerobic sulfate-reducing bacteria sludge system[J]. Water Research, 2019, 161: 191-201. doi: 10.1016/j.watres.2019.06.010
[47] JI J, KAKADE A, YU Z S, et al. Anaerobic membrane bioreactors for treatment of emerging contaminants: A review[J]. Journal of Environmental Management, 2020, 270: 110913. doi: 10.1016/j.jenvman.2020.110913
[48] XIE J, DUAN X, FENG L Y, et al. Influence of sulfadiazine on anaerobic fermentation of waste activated sludge for volatile fatty acids production: Focusing on microbial responses[J]. Chemosphere, 2019, 219: 305-312. doi: 10.1016/j.chemosphere.2018.12.015
[49] ZHENG W L, WEN X H, ZHANG B, et al. Selective effect and elimination of antibiotics in membrane bioreactor of urban wastewater treatment plant[J]. Science of The Total Environment, 2019, 646: 1293-1303. doi: 10.1016/j.scitotenv.2018.07.400
[50] WIJEKOON K C, MCDONALD J A, KHAN S J, et al. Development of a predictive framework to assess the removal of trace organic chemicals by anaerobic membrane bioreactor[J]. Bioresource Technology, 2015, 189: 391-398. doi: 10.1016/j.biortech.2015.04.034
[51] HUANG B, WANG H C, CUI D, et al. Treatment of pharmaceutical wastewater containing β-lactams antibiotics by a pilot-scale anaerobic membrane bioreactor (AnMBR)[J]. Chemical Engineering Journal, 2018, 341: 238-247. doi: 10.1016/j.cej.2018.01.149
[52] NG K K, SHI X Q, NG H Y. Evaluation of system performance and microbial communities of a bioaugmented anaerobic membrane bioreactor treating pharmaceutical wastewater[J]. Water Research, 2015, 81: 311-24. doi: 10.1016/j.watres.2015.05.033
[53] NG K K, SHI X Q, TANG M K Y, et al. A novel application of anaerobic bio-entrapped membrane reactor for the treatment of chemical synthesis-based pharmaceutical wastewater[J]. Separation and Purification Technology, 2014, 132: 634-643. doi: 10.1016/j.seppur.2014.06.021
[54] ZAREI-BAYGI A, HARB M, WANG P, et al. Evaluating antibiotic resistance gene correlations with antibiotic exposure conditions in anaerobic membrane bioreactors[J]. Environmental Science & Technology, 2019, 53(7): 3599-3609.
[55] HU D X, SU H Y, CHEN Z B, et al. Performance evaluation and microbial community dynamics in a novel AnMBR for treating antibiotic solvent wastewater[J]. Bioresource Technology, 2017, 243: 218-227. doi: 10.1016/j.biortech.2017.06.095
[56] XIAO Y Y, YAOHARI H, DE ARAUJO C, et al. Removal of selected pharmaceuticals in an anaerobic membrane bioreactor (AnMBR) with/without powdered activated carbon (PAC)[J]. Chemical Engineering Journal, 2017, 321: 335-345. doi: 10.1016/j.cej.2017.03.118
[57] LEIKNES T, AMY G, HOPPE-JONES C, et al. Organic micro-pollutants’ removal via anaerobic membrane bioreactor with ultrafiltration and nanofiltration[J]. Journal of Water Reuse and Desalination, 2016, 6(3): 362-370. doi: 10.2166/wrd.2015.138
[58] LI Y, HU Q, GAO D W. Dynamics of archaeal and bacterial communities in response to variations of hydraulic retention time in an integrated anaerobic fluidized-bed membrane bioreactor treating benzothiazole wastewater[J]. Archaea, 2018, 2018: 9210534.
[59] DUTTA K, LEE M Y, LAI W W, et al. Removal of pharmaceuticals and organic matter from municipal wastewater using two-stage anaerobic fluidized membrane bioreactor[J]. Bioresource Technology, 2014, 165: 42-9. doi: 10.1016/j.biortech.2014.03.054
[60] LE T H, NG C, TRAN N H, et al. Removal of antibiotic residues, antibiotic resistant bacteria and antibiotic resistance genes in municipal wastewater by membrane bioreactor systems[J]. Water Research, 2018, 145: 498-508. doi: 10.1016/j.watres.2018.08.060
[61] SCHWERMER C U, KRZEMINSKI P, WENNBERG A C, et al. Removal of antibiotic resistant e. Coli in two norwegian wastewater treatment plants and by nano- and ultra-filtration processes[J]. Water Science and Technology, 2017, 77(4): 1115-1126.
[62] ZHU Y J, WANG Y Y, ZHOU S, et al. Robust performance of a membrane bioreactor for removing antibiotic resistance genes exposed to antibiotics: Role of membrane foulants[J]. Water Research, 2018, 130: 139-150. doi: 10.1016/j.watres.2017.11.067
[63] NGUYEN T H, CHEN K L, ELIMELECH M. Adsorption kinetics and reversibility of linear plasmid DNA on silica surfaces: Influence of alkaline earth and transition metal ions[J]. Biomacromolecules, 2010, 11(5): 1225-1230. doi: 10.1021/bm901427n
[64] SAEKI K, KUNITO T, SAKAI M. Effects of pH, ionic strength, and solutes on DNA adsorption by andosols[J]. Biology and Fertility of Soils, 2010, 46(5): 531-535. doi: 10.1007/s00374-010-0447-y
[65] PEI M, ZHANG B, HE Y L, et al. State of the art of tertiary treatment technologies for controlling antibiotic resistance in wastewater treatment plants[J]. Environment International, 2019, 131: 105026. doi: 10.1016/j.envint.2019.105026
[66] CHENG H, HONG P Y. Removal of antibiotic-resistant bacteria and antibiotic resistance genes affected by varying degrees of fouling on anaerobic microfiltration membranes[J]. Environmental Science & Technology, 2017, 51(21): 12200-12209.
[67] WANG K M, ZHOU L X, MENG S H, et al. Anaerobic membrane bioreactor for real antibiotic pharmaceutical wastewater treatment: Positive effect of fouling layer on antibiotics and antibiotic resistance genes removals[J]. Journal of Cleaner Production, 2023, 409: 137234. doi: 10.1016/j.jclepro.2023.137234
[68] KAYA Y, BACAKSIZ A M, BAYRAK H, et al. Investigation of membrane fouling in an anaerobic membrane bioreactor (AnMBR) treating pharmaceutical wastewater[J]. Journal of Water Process Engineering, 2019, 31: 100822. doi: 10.1016/j.jwpe.2019.100822
[69] CHEN P, XIE Q L, ADDY M, et al. Utilization of municipal solid and liquid wastes for bioenergy and bioproducts production[J]. Bioresource Technology, 2016, 215: 163-172. doi: 10.1016/j.biortech.2016.02.094
[70] SHIMADA T, LI X, ZILLES J L, et al. Effects of the antimicrobial tylosin on the microbial community structure of an anaerobic sequencing batch reactor[J]. Biotechnology and Bioengineering, 2011, 108(2): 296-305. doi: 10.1002/bit.22934
[71] WANG S J, HOU X C, SU H J. Exploration of the relationship between biogas production and microbial community under high salinity conditions[J]. Scientific Reports, 2017, 7: 1149. doi: 10.1038/s41598-017-01298-y
[72] XIONG Y H, HARB M, HONG P Y. Performance and microbial community variations of anaerobic digesters under increasing tetracycline concentrations[J]. Applied Microbiology and Biotechnology, 2017, 101(13): 5505-5517. doi: 10.1007/s00253-017-8253-1
[73] BENERAGAMA N, LATEEF S A, IWASAKI M, et al. The combined effect of cefazolin and oxytertracycline on biogas production from thermophilic anaerobic digestion of dairy manure[J]. Bioresource Technology, 2013, 133: 23-30. doi: 10.1016/j.biortech.2013.01.032
[74] AYDIN S, INCE B, INCE O. Assessment of anaerobic bacterial diversity and its effects on anaerobic system stability and the occurrence of antibiotic resistance genes[J]. Bioresource Technology, 2016, 207: 332-338. doi: 10.1016/j.biortech.2016.01.080
[75] CETECIOGLU Z, INCE B, GROS M, et al. Chronic impact of tetracycline on the biodegradation of an organic substrate mixture under anaerobic conditions[J]. Water Research, 2013, 47(9): 2959-2969. doi: 10.1016/j.watres.2013.02.053
[76] PALA-OZKOK I, ORHON D. Chronic effect of erythromycin on substrate biodegradation kinetics of activated sludge[J]. Biochemical Engineering Journal, 2013, 81: 29-39. doi: 10.1016/j.bej.2013.10.002
[77] AMIN M M, ZILLES J L, GREINER J, et al. Influence of the antibiotic erythromycin on anaerobic treatment of a pharmaceutical wastewater[J]. Environental Science & Technology, 2006, 40(12): 3971-3977.
[78] TANG L, FENG H D, LUAN X, et al. Occurrence, distribution, and behaviors of erythromycin a, production byproducts, transformation products, and resistance genes in a full-scale erythromycin a production wastewater treatment system[J]. Water Research, 2023, 245: 120640. doi: 10.1016/j.watres.2023.120640
[79] CETECIOGLU Z, INCE B, ORHON D, et al. Acute inhibitory impact of antimicrobials on acetoclastic methanogenic activity[J]. Bioresource Technology, 2012, 114: 109-1016. doi: 10.1016/j.biortech.2012.03.020
[80] HU J W, XU Q X, LI X M, et al. Sulfamethazine (SMZ) affects fermentative short-chain fatty acids production from waste activated sludge[J]. Science of the Total Environment, 2018, 639: 1471-1479. doi: 10.1016/j.scitotenv.2018.05.264
[81] LU M Q, NIU X J, LIU W, et al. Biogas generation in anaerobic wastewater treatment under tetracycline antibiotic pressure[J]. Scientific Reports, 2016, 6: 28336. doi: 10.1038/srep28336
[82] HE Y P, TIAN Z, LUAN X, et al. Recovery of biological wastewater treatment system inhibited by oxytetracycline: Rebound of functional bacterial population and the impact of adsorbed oxytetracycline on antibiotic resistance[J]. Chemical Engineering Journal, 2021, 418: 129364. doi: 10.1016/j.cej.2021.129364
[83] FENG H D, HU Y Q, TANG L, et al. New hydrolysis products of oxytetracycline and their contribution to hard cod in biological effluents of antibiotic production wastewater[J]. Chemical Engineering Journal, 2023, 471: 144409. doi: 10.1016/j.cej.2023.144409
[84] RUSANOWSKA P, HARNISZ M, ZIELIŃSKI M, et al. Individual and synergistic effects of metronidazole, amoxicillin, and ciprofloxacin on methane fermentation with sewage sludge[J]. CLEAN-Soil Air Water, 2020, 48(2): 1900281. doi: 10.1002/clen.201900281
[85] CZATZKOWSKA M, HARNISZ M, KORZENIEWSKA E, et al. The impact of antimicrobials on the efficiency of methane fermentation of sewage sludge, changes in microbial biodiversity and the spread of antibiotic resistance[J]. Journal of Hazardous Materials, 2021, 416: 125773. doi: 10.1016/j.jhazmat.2021.125773
[86] CHENG D L, NGO H H, GUO W S, et al. Improving sulfonamide antibiotics removal from swine wastewater by supplying a new pomelo peel derived biochar in an anaerobic membrane bioreactor[J]. Bioresource Technology, 2021, 319: 124160. doi: 10.1016/j.biortech.2020.124160
[87] WEI C H, SANCHEZ-HUERTA C, LEIKNES T, et al. Removal and biotransformation pathway of antibiotic sulfamethoxazole from municipal wastewater treatment by anaerobic membrane bioreactor[J]. Journal of Hazardous Materials, 2019, 380: 120894. doi: 10.1016/j.jhazmat.2019.120894
[88] DO T M, CHOI D, OH S, et al. Anaerobic membrane bioreactor performance with varying feed concentrations of ciprofloxacin[J]. Science of the Total Environment, 2022, 803: 150108. doi: 10.1016/j.scitotenv.2021.150108
[89] WANG X H, ZHANG J F, CHANG V W C, et al. Removal of cytostatic drugs from wastewater by an anaerobic osmotic membrane bioreactor[J]. Chemical Engineering Journal, 2018, 339: 153-161. doi: 10.1016/j.cej.2018.01.125
[90] SHEN L G, LEI Q, CHEN J R, et al. Membrane fouling in a submerged membrane bioreactor: Impacts of floc size[J]. Chemical Engineering Journal, 2015, 269: 328-334. doi: 10.1016/j.cej.2015.02.002
[91] AUBENNEAU M, TAHAR A, CASELLAS C, et al. Membrane bioreactor for pharmaceutically active compounds removal: Effects of carbamazepine on mixed microbial communities implied in the treatment[J]. Process Biochemistry, 2010, 45(11): 1826-1831. doi: 10.1016/j.procbio.2010.04.011
[92] JUNTAWANG C, RONGSAYAMANONT C, KHAN E. Entrapped cells-based-anaerobic membrane bioreactor treating domestic wastewater: Performances, fouling, and bacterial community structure[J]. Chemosphere, 2017, 187: 147-155. doi: 10.1016/j.chemosphere.2017.08.113
[93] LI B, YANG Y, MA L, et al. Metagenomic and network analysis reveal wide distribution and co-occurrence of environmental antibiotic resistance genes[J]. The ISME Journal, 2015, 9(11): 2490-502. doi: 10.1038/ismej.2015.59
[94] ZAREI-BAYGI A, HARB M, WANG P, et al. Microbial community and antibiotic resistance profiles of biomass and effluent are distinctly affected by antibiotic addition to an anaerobic membrane bioreactor[J]. Environmental Science:Water Research & Technology, 2020, 6(3): 724-736.
[95] COSTA B F, ZAREI-BAYGI A, MD ISKANDER S, et al. Antibiotic resistance genes fate during food waste management-comparison between thermal treatment, hyperthermophilic composting, and anaerobic membrane bioreactor[J]. Bioresource Technology, 2023, 388: 129771. doi: 10.1016/j.biortech.2023.129771
[96] CUI T T, ZHANG S Y, YE J Y, et al. Distribution, dissemination and fate of antibiotic resistance genes during sewage sludge processing-a review[J]. Water Air & Soil Pollution, 2022, 233(4): 138.
[97] World Health Organization. Technical brief on water, sanitation, hygiene and wastewater management to prevent infections and reduce the spread of antimicrobial resistance. Geneva: World health organization[DB/OL]. [2020-11-18]https://www.who.int/publications/i/item/9789240006416.
[98] 聂宇, 陈娅婷, 孙照勇, 等. 污水/城市污泥中抗生素对厌氧消化的影响研究进展[J]. 应用与环境生物学报, 2020, 26(2): 479-488.
[99] GóMEZ-PACHECO C V, SáNCHEZ-POLO M, RIVERA-UTRILLA J, et al. Tetracycline removal from waters by integrated technologies based on ozonation and biodegradation[J]. Chemical Engineering Journal, 2011, 178: 115-121. doi: 10.1016/j.cej.2011.10.023
[100] TANG M, LI F, YANG M, et al. Degradation of kanamycin from production wastewater with high-concentration organic matrices by hydrothermal treatment[J]. Journal of Environmental Sciences, 2020, 97: 11-18. doi: 10.1016/j.jes.2020.04.032
[101] YI Q Z, GAO Y X, ZHANG H F, et al. Establishment of a pretreatment method for tetracycline production wastewater using enhanced hydrolysis[J]. Chemical Engineering Journal, 2016, 300: 139-145. doi: 10.1016/j.cej.2016.04.120
[102] 张昱, 唐妹, 田哲, 等. 制药废水中抗生素的去除技术研究进展[J]. 环境工程学报, 2018, 12(1): 1-14.
[103] HE Y P, TIAN Z, YI Q Z, et al. Impact of oxytetracycline on anaerobic wastewater treatment and mitigation using enhanced hydrolysis pretreatment[J]. Water Research, 2020, 187: 116408. doi: 10.1016/j.watres.2020.116408
[104] TIAN Y, TIAN Z, FENG H D, et al. Unveiling the threshold values of organic and oxytetracycline loadings for nitrification recovery of a full-scale pharmaceutical wastewater treatment system[J]. Chemical Engineering Journal, 2023, 463: 142487. doi: 10.1016/j.cej.2023.142487
[105] TIAN Y, TIAN Z, HE Y P, et al. Removal of denatured protein particles enhanced uasb treatment of oxytetracycline production wastewater[J]. Science of the Total Environment, 2022, 816: 151549. doi: 10.1016/j.scitotenv.2021.151549
[106] TANG M, GU Y, WEI D B, et al. Enhanced hydrolysis of fermentative antibiotics in production wastewater: Hydrolysis potential prediction and engineering application[J]. Chemical Engineering Journal, 2020, 391: 123626. doi: 10.1016/j.cej.2019.123626
[107] 田野. 基于强化水解预处理的土霉素生产废水处理工艺研究[D]. 北京: 中国科学院生态环境研究中心, 2023.
[108] WU D N, DAI S T, FENG H D, et al. Persistence and potential risks of tetracyclines and their transformation products in two typical different animal manure composting treatments[J]. Environmental Pollution, 2024, 341: 122904. doi: 10.1016/j.envpol.2023.122904
[109] DUNCAN J, BOKHARY A, FATEHI P, et al. Thermophilic membrane bioreactors: A review[J]. Bioresource Technology, 2017, 243: 1180-1193. doi: 10.1016/j.biortech.2017.07.059
[110] JANG H M, SHIN J, CHOI S, et al. Fate of antibiotic resistance genes in mesophilic and thermophilic anaerobic digestion of chemically enhanced primary treatment (CEPT) sludge[J]. Bioresource Technology, 2017, 244: 433-444. doi: 10.1016/j.biortech.2017.07.153
[111] 马清佳, 田哲, 员建, 等. 9种抗生素对污泥高温厌氧消化的急性抑制[J]. 环境工程学报, 2018, 12(7): 2084-2093.
[112] TIAN Z, CHI Y Z, YU B, et al. Thermophilic anaerobic digestion reduces args in excess sludge even under high oxytetracycline concentrations[J]. Chemosphere, 2019, 222: 305-313. doi: 10.1016/j.chemosphere.2019.01.139
[113] ASLAM M, CHARFI A, LESAGE G, et al. Membrane bioreactors for wastewater treatment: A review of mechanical cleaning by scouring agents to control membrane fouling[J]. Chemical Engineering Journal, 2017, 307: 897-913. doi: 10.1016/j.cej.2016.08.144
[114] NGUYEN T T, BUI X T, LUU V P, et al. Removal of antibiotics in sponge membrane bioreactors treating hospital wastewater: Comparison between hollow fiber and flat sheet membrane systems[J]. Bioresource Technology, 2017, 240: 42-49. doi: 10.1016/j.biortech.2017.02.118
[115] ZHANG W X, TANG B, BIN L Y. Research progress in biofilm-membrane bioreactor: A critical review[J]. Industrial & Engineering Chemistry Research, 2017, 56(24): 6900-6909.
[116] LI Z H, YUAN L, YANG C W, et al. Anaerobic electrochemical membrane bioreactor effectively mitigates antibiotic resistance genes proliferation under high antibiotic selection pressure[J]. Environment International, 2022, 166: 107381. doi: 10.1016/j.envint.2022.107381
[117] LI Z H, YUAN L, GENG Y K, et al. Evaluating the effect of gradient applied voltages on antibiotic resistance genes proliferation and biogas production in anaerobic electrochemical membrane bioreactor[J]. Journal of Hazardous Materials, 2021, 416: 125865. doi: 10.1016/j.jhazmat.2021.125865
[118] DING A Q, FAN Q, CHENG R, et al. Impacts of applied voltage on microbial electrolysis cell-anaerobic membrane bioreactor (MEC-AnMBR) and its membrane fouling mitigation mechanism[J]. Chemical Engineering Journal, 2018, 333: 630-635. doi: 10.1016/j.cej.2017.09.190