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氧氟沙星和诺氟沙星的水环境光化学转化: pH值及溶解性物质的影响

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尉小旋, 陈景文, 王如冰, 郭芳婕, 曾宇飞, 李雨昕, 吴英格. 氧氟沙星和诺氟沙星的水环境光化学转化: pH值及溶解性物质的影响[J]. 环境化学, 2015, 34(3): 448-454. doi: 10.7524/j.issn.0254-6108.2015.03.2014061808
引用本文: 尉小旋, 陈景文, 王如冰, 郭芳婕, 曾宇飞, 李雨昕, 吴英格. 氧氟沙星和诺氟沙星的水环境光化学转化: pH值及溶解性物质的影响[J]. 环境化学, 2015, 34(3): 448-454. doi: 10.7524/j.issn.0254-6108.2015.03.2014061808
shu
WEI Xiaoxuan, CHEN Jingwen, WANG Rubing, GUO Fangjie, ZENG Yufei, LI Yuxin, WU Yingge. Aquatic photochemical transformation of ofloxacin and norfloxacin: Effects of pH and water constituents[J]. Environmental Chemistry, 2015, 34(3): 448-454. doi: 10.7524/j.issn.0254-6108.2015.03.2014061808
Citation: WEI Xiaoxuan, CHEN Jingwen, WANG Rubing, GUO Fangjie, ZENG Yufei, LI Yuxin, WU Yingge. Aquatic photochemical transformation of ofloxacin and norfloxacin: Effects of pH and water constituents[J]. Environmental Chemistry, 2015, 34(3): 448-454. doi: 10.7524/j.issn.0254-6108.2015.03.2014061808
shu

氧氟沙星和诺氟沙星的水环境光化学转化: pH值及溶解性物质的影响

  • 1.

    大连理工大学环境学院工业生态与环境工程教育部重点实验室, 大连, 116024

  • 基金项目:

    国家重点基础研究计划(973计划)课题(2013CB430403)

    国家自然科学基金(21137001)资助.

Aquatic photochemical transformation of ofloxacin and norfloxacin: Effects of pH and water constituents

  • 1.

    Key Laboratory of Industrial Ecology and Environmental Engineering (MOE), School of Environmental Science and Technology, Dalian University of Technology, Dalian, 116024, China

  • Fund Project:

  • 摘要: 在模拟日光照射下,考察了氧氟沙星和诺氟沙星在纯水和天然水中的光降解行为,结果表明,氧氟沙星和诺氟沙星的光降解随pH增加(pH=4—10)先增快后减慢,两种抗生素以两性离子形态存在时光解最快.氧氟沙星和诺氟沙星在天然水中的光降解显著慢于其在相似pH条件下(pH=8)纯水中的光降解,天然水中的溶解性物质对两种抗生素的光降解总体表现为抑制作用.以Suwannee河富里酸为例,研究了溶解性有机质(DOM)的影响机制,发现淡水中高浓度的DOM主要通过竞争光吸收抑制氧氟沙星和诺氟沙星的光解,而海水中低浓度的DOM可以通过淬灭活性物种抑制两种抗生素的光解.天然水中的金属阳离子(Ca2+和Fe3+)和NO3-分别通过配位作用和光致生成·OH影响氧氟沙星和诺氟沙星的降解.由此可见,氧氟沙星和诺氟沙星在天然水中的光化学行为依赖于水体pH值和溶解性物质的综合影响.
    Abstract: The photochemical transformation of ofloxacin and norfloxacin in pure and natural water was investigated under the simulated sunlight irradiation. The results show that the photolytic rate constants of ofloxacin and norfloxacin increased to a peak and then decreased with pH increasing from 4 to 10. Ofloxacin and norfloxacin in zwitter ionic forms photodegraded the fastest. The photodegradation rates of ofloxacin and norfloxacin in natural water were slower than that in pure water with similar pH condition (pH=8). The water constituents in natural water played an inhibiting role. The Suwannee River fulvic acid was adopted as a model to investigate the effect mechanisms of dissolved organic matter (DOM). The results show that high concentration DOM in freshwater slowed the photodegradation of ofloxacin and norfloxacin mainly by competitive light absorption, and the inhibition of low concentration DOM in seawater is due to the quenching of reactive species photogenerated by antibiotics. Metal cations (e.g., Ca2+ and Fe3+) and NO3- in natural water affected the photodegradation of ofloxacin and norfloxacin by complexation and photogeneration of ·OH, respectively. Thus, the photodegradation of ofloxacin and norfloxacin in natural water depends on the integrative influence of pH and the water constituents.
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  • [1] Segura P A, Francois M, Gagnon C, et al. Review of the occurrence of anti-infectives in contaminated wastewaters and natural and drinking waters[J]. Environmental Health Perspectives, 2009, 117(5): 675-684
    [2] Larsson D G J, De Pedro C, Paxeus N. Effluent from drug manufactures contains extremely high levels of pharmaceuticals[J]. Journal of Hazardous Materials, 2007, 148(3):751-755
    [3] Yiruhan, Wang Q J, Mo C H, et al. Determination of four fluoroquinolone antibiotics in tap water in Guangzhou and Macao[J]. Environmental Pollution, 2010, 158(7): 2350-2358
    [4] Gullberg E, Cao S, Berg O G, et al. Selection of resistant bacteria at very low antibiotic concentrations[J]. PLoS Pathogens, 2011, 7(7): e1002158
    [5] Hu J Y, Wang W, Zhu Z, et al. Quantitative structure-Activity relationship model for prediction of genotoxic potential for quinolone antibacterials[J]. Environment Science & Technology, 2007, 41(13): 4806-4812
    [6] Ge L K, Chen J W, Wei X X, et al. Aquatic photochemistry of fluoroquinolone antibiotics: Kinetics, pathways, and multivariate effects of main water constituents[J]. Environment Science & Technology, 2010, 44(7): 2400-2405
    [7] Li Y, Niu J F, Wang W L. Photolysis of enrofloxacin in aqueous systems under simulated sunlight irradiation: Kinetics, mechanism and toxicity of photolysis products[J]. Chemosphere, 2011, 85(5): 892-897
    [8] Sturini M, Speltini A, Maraschi F, et al. Photodegradation of fluoroquinolones in surface water and antimicrobial activity of the photoproducts[J]. Water Research 2012, 46(17): 5575-5582
    [9] 葛林科, 张思玉, 谢晴, 等. 抗生素在水环境中的光化学行为研究进展[J]. 中国科学: 化学, 2010, 40(2): 124-135
    [10] Ge L K, Chen J W, Lin J, et al. Light-source-dependent effects of main water constituents on photodegradation of phenicol antibiotics: Mechanism and kinetics[J]. Environment Science & Technology, 2009, 43(9): 3101-3107
    [11] Chen Y, Hu C, Qu J H, et al. Photodegradation of tetracycline and formation of reactive oxygen species in aqueous tetracycline solution under simulated sunlight irradiation[J]. Journal of Photochemistry and Photobiology A: Chemistry, 2008,197(1): 81-87
    [12] Boreen A L, Arnold W A, McNeill K. Photochemical fate of sulfa drugs in the aquatic environment: Sulfa drugs containing five-membered heterocyclic groups[J]. Environment Science & Technology, 2004, 38(14): 3933-3940
    [13] Boreen A L, Arnold W A, McNeill K. Triplet-sensitized photodegradation of sulfa drugs containing six-membered heterocyclic groups: Identification of an SO2 extrusion photoproduct[J]. Environment Science & Technology, 2005, 39(10): 3630-3638
    [14] Werner J J, Arnold W A, McNeill K. Water hardness as a photochemical parameter: Tetracycline photolysis as a function of calcium concentration, magnesium concentration, and pH[J]. Environment Science & Technology, 2006, 40(23): 7236-7241
    [15] Zhou D N, Huang W Y, Wu F, et al. Photodegradation of chloromycetin in aqueous solutions: Kinetics and influencing factors[J]. Reaction Kinetics, Mechanisms and Catalysis, 2010, 100(1): 45-53
    [16] Vione D, Feitosa-Felizzola J, Minero C, et al. Phototransformation of selected human-used macrolides in surface water: Kinetics, model predictions and degradation pathways[J]. Water Research, 2009, 43(7): 1959-1967
    [17] 大连理工大学无机化学教研室编. 无机化学(第5版) [M]. 北京: 高等教育出版社, 2006: 691
    [18] Xie Q, Chen J W, Zhao H X, et al. Different photolysis kinetics and photooxidation reactivities of neutral and anionic hydroxylated polybrominated diphenyl ethers[J]. Chemosphere, 2013, 90 (2): 188-194
    [19] Espinoza L A T, Neamtu M, Frimmel F H. The effect of nitrate, Fe(Ⅲ) and bicarbonate on the degradation of bisphenol A by simulated solar UV-irradiation[J]. Water Research, 2007, 41(19): 4479-4487
    [20] Qiang Z M, Adams C. Potentiometric determination of acid dissociation constants (pKa) for human and veterinary antibiotics[J]. Water Research, 2004, 38(12): 2874-2890
    [21] Wei X X, Chen J W, Xie Q, et al. Distinct photolytic mechanisms and products for different dissociation species of ciprofloxacin[J]. Environment Science & Technology, 2013, 47(9): 4284-4290
    [22] Wenk J, von Gunten U, Canonica S. Effect of dissolved organic matter on the transformation of contaminants induced by excited triplet states and the hydroxyl radical[J]. Environment Science & Technology, 2011, 45(4): 1334-1340
    [23] Jiao S J, Zheng S R, Yin D Q, et al. Aqueous photolysis of tetracycline and toxicity of photolytic products to luminescent bacteria[J]. Chemosphere, 2008,73(3): 377-382
    [24] Park H R, Chung K Y, Lee H C, et al. Ionization and divalent cation complexation of quinolone antibiotics in aqueous solution[J]. Bulletin of the Korean Chemical Society, 2000, 21(9):849-854
    [25] Urbaniak B, Mrestani Y, Kokot Z J, et al. Investigation of interaction of fluoroquinolones with aluminum, iron and magnesium ions using capillary zone eletrophoresis[J]. Chromatographia, 2007, 65(7/8): 489-492
    [26] Haag W R, Yao C C D. Rate constants for reaction of hydroxyl radicals with several drinking-water contaminants[J]. Environmental Science & Technology, 1992, 26(5): 1005-1013
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  • 收稿日期:  2014-06-18
  • 刊出日期:  2015-03-15
尉小旋, 陈景文, 王如冰, 郭芳婕, 曾宇飞, 李雨昕, 吴英格. 氧氟沙星和诺氟沙星的水环境光化学转化: pH值及溶解性物质的影响[J]. 环境化学, 2015, 34(3): 448-454. doi: 10.7524/j.issn.0254-6108.2015.03.2014061808
引用本文: 尉小旋, 陈景文, 王如冰, 郭芳婕, 曾宇飞, 李雨昕, 吴英格. 氧氟沙星和诺氟沙星的水环境光化学转化: pH值及溶解性物质的影响[J]. 环境化学, 2015, 34(3): 448-454. doi: 10.7524/j.issn.0254-6108.2015.03.2014061808
shu
WEI Xiaoxuan, CHEN Jingwen, WANG Rubing, GUO Fangjie, ZENG Yufei, LI Yuxin, WU Yingge. Aquatic photochemical transformation of ofloxacin and norfloxacin: Effects of pH and water constituents[J]. Environmental Chemistry, 2015, 34(3): 448-454. doi: 10.7524/j.issn.0254-6108.2015.03.2014061808
Citation: WEI Xiaoxuan, CHEN Jingwen, WANG Rubing, GUO Fangjie, ZENG Yufei, LI Yuxin, WU Yingge. Aquatic photochemical transformation of ofloxacin and norfloxacin: Effects of pH and water constituents[J]. Environmental Chemistry, 2015, 34(3): 448-454. doi: 10.7524/j.issn.0254-6108.2015.03.2014061808
shu

氧氟沙星和诺氟沙星的水环境光化学转化: pH值及溶解性物质的影响

  • 1. 大连理工大学环境学院工业生态与环境工程教育部重点实验室, 大连, 116024
  • 收稿日期:  2014-06-18
基金项目:

国家重点基础研究计划(973计划)课题(2013CB430403)

国家自然科学基金(21137001)资助.

摘要: 在模拟日光照射下,考察了氧氟沙星和诺氟沙星在纯水和天然水中的光降解行为,结果表明,氧氟沙星和诺氟沙星的光降解随pH增加(pH=4—10)先增快后减慢,两种抗生素以两性离子形态存在时光解最快.氧氟沙星和诺氟沙星在天然水中的光降解显著慢于其在相似pH条件下(pH=8)纯水中的光降解,天然水中的溶解性物质对两种抗生素的光降解总体表现为抑制作用.以Suwannee河富里酸为例,研究了溶解性有机质(DOM)的影响机制,发现淡水中高浓度的DOM主要通过竞争光吸收抑制氧氟沙星和诺氟沙星的光解,而海水中低浓度的DOM可以通过淬灭活性物种抑制两种抗生素的光解.天然水中的金属阳离子(Ca2+和Fe3+)和NO3-分别通过配位作用和光致生成·OH影响氧氟沙星和诺氟沙星的降解.由此可见,氧氟沙星和诺氟沙星在天然水中的光化学行为依赖于水体pH值和溶解性物质的综合影响.

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