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基于液相色谱法分析水环境中大环内酯类抗生素污染的研究进展

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章琴琴, 汪昆平, 杨林, 徐乾前, 刘苗苗. 基于液相色谱法分析水环境中大环内酯类抗生素污染的研究进展[J]. 环境化学, 2012, 31(11): 1787-1796.
引用本文: 章琴琴, 汪昆平, 杨林, 徐乾前, 刘苗苗. 基于液相色谱法分析水环境中大环内酯类抗生素污染的研究进展[J]. 环境化学, 2012, 31(11): 1787-1796.
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ZHANG Qinqin, WANG Kunping, YANG Lin, XU Qianqian, LIU Miaomiao. Determination of macrolide antibiotic residues in water environment based on the liquid chromatography: A review[J]. Environmental Chemistry, 2012, 31(11): 1787-1796.
Citation: ZHANG Qinqin, WANG Kunping, YANG Lin, XU Qianqian, LIU Miaomiao. Determination of macrolide antibiotic residues in water environment based on the liquid chromatography: A review[J]. Environmental Chemistry, 2012, 31(11): 1787-1796.
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基于液相色谱法分析水环境中大环内酯类抗生素污染的研究进展

  • 1.

    重庆大学城市建设与环境工程学院, 重庆, 400030

Determination of macrolide antibiotic residues in water environment based on the liquid chromatography: A review

  • 1.

    College of Urban Construction & Environment Engineering, Chongqing University, Chongqing, 400030, China

  • 摘要: 大环内酯抗生素广泛使用,在水环境中的残留越来越引起世界关注.本文综述了国内外基于液相色谱技术分析水环境中大环内酯的方法,比较不同预处理法以及分析方法的灵敏度和检出限.固相萃取法可以同时富集和净化,消耗试剂少,方便,野外操作可行,是理想的预处理技术.液相色谱串联质谱技术选择性好、特异性高、灵敏度高,可以检测浓度低于ng·L-1的目标物,是一种可靠理想的分析方法.最后对大环内酯分析研究进行了展望.
    Abstract: Macrolide antibiotic is widespread used throughout the world as one kind of typical antibiotics. Because of its huge usage, there is high residue in environment. Macrolide antibiotic leads to microbial resistance and does harm to organisms in water by producing acute and chronic toxicity. It is necessary to strengthen analysis and research of the risk from macrolide antibiotics. This article reviewed the analysis methods for determining macrolide antibiotics using high performance liquid chromatography-mass spectrometry in water environment. At the same time, different pretreatments and detection methods were compared in terms of their sensitivity and detection limits, and detection of macrolide antibiotics in water environment was prospected in the future.
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  • 收稿日期:  2011-08-25
章琴琴, 汪昆平, 杨林, 徐乾前, 刘苗苗. 基于液相色谱法分析水环境中大环内酯类抗生素污染的研究进展[J]. 环境化学, 2012, 31(11): 1787-1796.
引用本文: 章琴琴, 汪昆平, 杨林, 徐乾前, 刘苗苗. 基于液相色谱法分析水环境中大环内酯类抗生素污染的研究进展[J]. 环境化学, 2012, 31(11): 1787-1796.
shu
ZHANG Qinqin, WANG Kunping, YANG Lin, XU Qianqian, LIU Miaomiao. Determination of macrolide antibiotic residues in water environment based on the liquid chromatography: A review[J]. Environmental Chemistry, 2012, 31(11): 1787-1796.
Citation: ZHANG Qinqin, WANG Kunping, YANG Lin, XU Qianqian, LIU Miaomiao. Determination of macrolide antibiotic residues in water environment based on the liquid chromatography: A review[J]. Environmental Chemistry, 2012, 31(11): 1787-1796.
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基于液相色谱法分析水环境中大环内酯类抗生素污染的研究进展

  • 1. 重庆大学城市建设与环境工程学院, 重庆, 400030
  • 收稿日期:  2011-08-25

摘要: 大环内酯抗生素广泛使用,在水环境中的残留越来越引起世界关注.本文综述了国内外基于液相色谱技术分析水环境中大环内酯的方法,比较不同预处理法以及分析方法的灵敏度和检出限.固相萃取法可以同时富集和净化,消耗试剂少,方便,野外操作可行,是理想的预处理技术.液相色谱串联质谱技术选择性好、特异性高、灵敏度高,可以检测浓度低于ng·L-1的目标物,是一种可靠理想的分析方法.最后对大环内酯分析研究进行了展望.

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