摘要:
多溴联苯醚(polybrominated diphenyl ethers, PBDEs)作为一种高效、添加型阻燃剂被广泛使用,因其具有蒸汽压低、亲脂性强、污染持久和可生物富集等特点,而成为近年来环境领域研究热点之一。在查阅近年相关文献和分析PBDEs性质的基础上,本文以PBDEs使用-环境分布-生物体内的分布-对生物毒性及机理为线索,重点总结了PBDEs在环境和尤其是在生物体内的分布情况,并分别从神经系统、甲状腺和肝脏等角度阐述了PBDEs产生毒性效应以及致毒机制的最新研究成果。在总结研究成果的基础上,提出了应逐渐重视十溴联苯醚的环境风险、电子垃圾拆解地PBDEs修复、PBDEs代谢过程以及代谢中间物的毒性等建议,以期为PBDEs相关领域研究者提供参考。
Abstract:
As an efficient flame retardant additive, polybrominated diphenyl ethers (PBDEs) have been used in a wide range of commercial products. PBDEs are highly lipophilic, degradation resistant, bio-accumulative with low saturated vapor pressure. These special properties have made PBDEs a research focus in environmental disciplines in the past few years. Based on recent publications and the characteristic analysis of PBDEs, the distributions of PBDEs in natural environments and organisms were illustrated. Moreover, the toxic effect (e.g. neurotoxicity, thyrotoxicosis, hepatotoxicity, etc.) of PBDEs on organisms, as well as its toxicological mechanisms, were prominently summarized in the present study, following a path of “PBDEs application–environmental distribution–toxicological behavior in organisms–bio-toxicity”. More critical studies need to be conducted in the future, including the potential risk of BDE-209, the remedy of former e-waste recycling sites, and the exploration of PBDEs metabolism and the toxicity of metabolites. They may serve as meaningful references for researchers in relative fields.
点击查看大图
下载:
